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A mescaline analog with a propyl substitution on the 4-position
Documented in PiHKAL by Alexander Shulgin
Purity Level
≥ 99.5%
Independently lab-tested to meet research standards
Certificate of Analysis (COA) available on request
Appearance
White crystalline powder
Fine, odorless, easily measured
Packaged in light-resistant, airtight containers
Molecular Formula
C13H21NO3
Chemical structure information
Useful for research references
Molecular Weight
239.31 g/mol
Indicates molar mass per mole of compound
Relevant for lab calculations
CAS Number
28830-19-9
Unique identifier used in chemical indexing
Helps with regulatory and import classification
Solubility
Soluble in ethanol, DMSO
Practically insoluble in water
Use compatible solvents for solution-based research
Melting Point
149–151 °C (approximate)
Physical identification property
May vary slightly based on batch
Storage Conditions
2°C–8°C (Refrigerated)
Best preserved in cool, dark, and dry environment
Avoid direct sunlight and humidity
Shelf Life
Up to 24 months when sealed
Degradation possible if improperly stored
Do not freeze
Packaging Options
250mg, 500mg, 1g, 2g, 5g
All sizes vacuum-sealed and labeled discreetly
Custom amounts available on inquiry
Legal Status
Varies by jurisdiction
Not scheduled under UN conventions in most regions
Subject to analog laws in some countries
Product Comparison Table
Compound
Proscaline
Mescaline
TMA-2
2C-E
Chemical Class
Phenethylamine
Phenethylamine
Phenethylamine
Phenethylamine
Active Duration
10–16 hours
8–12 hours
6–10 hours
6–10 hours
Subjective Intensity
Moderate to strong
Mild to moderate
Strong
Strong
Onset Time
1–2 hours
1–2 hours
30–60 minutes
30–90 minutes
Structure
4-propoxy-3,5-dimethoxy-PEA
3,4,5-trimethoxy-PEA
3,4,5-trimethoxyamphetamine
4-ethyl-2,5-dimethoxyphenethylamine
Legal Status
Often unscheduled
Widely controlled
Controlled in most countries
Controlled in some countries
Use Case
Research chemical
Traditional entheogen
Laboratory and experimental use
Research and limited entheogenic use
Visual Effects
Rich visuals and color enhancement
Dreamlike visuals and serenity
Fast visuals with stimulation
Patterned visuals and cognitive depth
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Unmatched Reliability We have a proven history of delivering rare compounds safely and discreetly across the globe. Our processes are streamlined to minimize delays and errors.
Industry-Leading Purity Standards Our Proscaline is ≥99.5% pure and professionally lab-analyzed. We never distribute substandard or unverified materials — quality is our foundation.
Absolute Privacy & Discretion Every order is packed in generic, unmarked containers. We never use labels that reveal product contents or your research interests.
Rapid Fulfillment & Global Delivery With 24-hour processing and overnight/express shipping, you can get what you need when you need it, wherever you are.
Flexible, Anonymous Payment Options We support cryptocurrency and other private methods that prioritize your confidentiality and transaction security.
Transparent Refund Policy If a package is lost, damaged, or seized, we’ll reship or refund — no hassle, no stress. We stand by our service from order to delivery.
Expert Customer Support Our team is here to help you with documentation, tracking, or chemical inquiries. We don’t just sell — we support your research journey.
Shipping Policy
At Psycho Plug, our shipping process is designed for speed, safety, and total anonymity. Every package is treated with utmost care from warehouse to your doorstep.
Worldwide Shipping Coverage We ship Proscaline globally, including the US, UK, EU, Canada, Australia, and many more. Local restrictions may apply, so verify your country’s laws before ordering.
Overnight and Express Options In many regions, we offer overnight delivery. For international shipments, express services typically take 3–7 business days.
Secure and Stealth Packaging All orders are sealed in tamper-evident, smell-proof, unbranded packaging. Labels never indicate product names or our store’s identity.
Tracking Number Provided Once your order is dispatched, you’ll receive tracking details immediately. You can monitor your package in real-time until it’s delivered.
30-Day Protection Guarantee If your item is lost, delayed, seized, or damaged in transit, we offer a no-questions-asked refund or a full reshipment within 30 days.
No Signature Required Most shipments do not require a signature, reducing the chance of delays or exposure during delivery.
Support and Assistance If you experience any issues with customs, transit, or delivery, our customer support is here to help — fast, friendly, and reliable.
Proscaline FAQ
Proscaline is a synthetic psychedelic compound belonging to the phenethylamine class. It is structurally and functionally related to mescaline and is valued in the research community for its extended duration, visual effects, and psychotropic properties. It is primarily used in scientific and analytical studies.
Chemical Background Proscaline is formally known as 4-propoxy-3,5-dimethoxyphenethylamine, a structural analog of mescaline with a propyl group replacing mescaline’s methoxy group on the 4-position of the phenyl ring.
First Documented in PiHKAL This compound was synthesized and reported by Alexander Shulgin in the book PiHKAL (Phenethylamines I Have Known and Loved), where its pharmacological profile and subjective effects were described.
Classification It is classified as a substituted phenethylamine — a category that includes several well-known psychedelics. Proscaline differs slightly in potency and duration due to its unique substitution pattern.
Research Use Only Proscaline is strictly intended for laboratory research, forensic analysis, and chemical study. It is not approved for human consumption, ingestion, or therapeutic use.
Physical Form It typically comes as a white or off-white crystalline powder with a fine consistency, facilitating accurate measurement for analytical studies.
Mechanism of Action Though specific studies are limited, Proscaline is believed to act as a 5-HT2A receptor agonist, similarly to mescaline and LSD, contributing to its psychedelic effects.
Proscaline is known in laboratory research for producing intense visual, emotional, and sensory changes, making it valuable for examining altered states of consciousness and neurochemical modulation.
Visual Alterations Studies report visual patterning, color enhancement, tracers, and shifting geometry. These effects can resemble mescaline but with a slower onset and longer duration.
Euphoria and Emotional Elevation Research documents a significant uplift in mood and emotional openness, often measured through subjective scales in cognitive studies.
Increased Sensory Perception Audio, tactile, and olfactory sensations are commonly heightened, offering insights into sensory gating and neural processing.
Time Dilation Subjects frequently report altered perception of time, where minutes may feel extended or non-linear — useful for studying temporal cognition.
Cognitive Expansion Increased introspection, recursive thought loops, and novel associative thinking patterns have been observed in monitored sessions.
Body Load and Energetic Shifts Physiological responses such as tingling, energy waves, or mild muscle tension are sometimes noted in reports, depending on dosage.
Afterglow Post-experience effects such as mental clarity or emotional grounding can persist for several hours or days in some studies.
The legal status of Proscaline varies by jurisdiction. It is not scheduled under most international drug control conventions, but it may still fall under analog or psychoactive substance regulations in specific countries.
Unscheduled in Most Regions In many countries, Proscaline is not specifically listed as a controlled substance, allowing it to be sold for research purposes.
Subject to Analog Acts In the United States and some European countries, it may be considered an analog of mescaline and thus regulated under analog laws if intended for human use.
Research Exemption Scientific use of Proscaline for non-consumptive purposes is typically permitted, provided that the product is not marketed or labeled for ingestion.
Buyer’s Responsibility Customers are responsible for knowing their local regulations before purchasing. Psycho Plug does not provide legal advice or guarantee import approval.
Shipping Restrictions We do not ship to regions where Proscaline is known to be restricted or banned. Our system flags high-risk zones to prevent legal complications.
Import Requirements In some countries, importation of research chemicals may require documentation, a license, or customs pre-clearance.
Proscaline is active in relatively low amounts. Accurate measurement is essential for any scientific or forensic study involving this compound.
Active Research Range Common research studies explore quantities from 20mg to 60mg, with effects becoming notably pronounced after 30mg.
Microdosing Observations Some lab protocols document microdosing quantities under 10mg to observe threshold-level interactions.
Always Use a Milligram Scale Due to its high potency, Proscaline must be weighed using a precise 0.001g (1mg) scale to avoid significant measurement errors.
Titration Recommended Begin studies at the lowest measurable amount and gradually increase based on objectives, sensitivity testing, or analytic feedback.
Form of Administration In laboratory environments, it may be dissolved in a compatible solvent (such as ethanol) for liquid measurement or capsule-filled for controlled release studies.
Lab Safety Compliance Any research involving active doses must comply with chemical handling, safety protocols, and institutional review requirements.
Proscaline’s chemical structure is based on the phenethylamine skeleton, with modifications that influence its receptor activity and pharmacological properties.
Molecular Formula: C13H21NO3 This denotes 13 carbon atoms, 21 hydrogen atoms, 1 nitrogen atom, and 3 oxygen atoms.
IUPAC Name: 2-(4-propoxy-3,5-dimethoxyphenyl)ethanamine This name reflects its substitution pattern and ethylamine base chain.
CAS Number: 28830-19-9 This unique identifier is used globally for tracking and regulatory purposes.
Molecular Weight: 239.31 g/mol Useful for stoichiometric calculations and molecular mass confirmation.
Functional Groups: The molecule contains two methoxy groups (–OCH₃) and one propoxy group (–OC₃H₇), which increase lipid solubility and alter receptor binding affinity.
Comparison to Mescaline Structurally, Proscaline replaces mescaline’s methyl group at the 4-position with a propyl chain, resulting in longer-lasting and slightly altered psychoactivity.
Solubility Characteristics It is non-polar and soluble in organic solvents like ethanol or DMSO, but poorly soluble in water.
Proper storage ensures the stability and longevity of Proscaline, preserving its chemical integrity over time.
Temperature Range Store between 2°C and 8°C (refrigerated). Prolonged exposure to room temperature or higher can degrade potency.
Moisture Control Avoid humid environments. Use desiccant packs to absorb excess moisture inside containers.
Light Sensitivity Keep the compound away from direct sunlight or UV sources. Light can break down molecular bonds and reduce effectiveness.
Container Type Use airtight, light-resistant containers like amber glass vials or vacuum-sealed mylar bags for optimal protection.
Avoid Freezing Freezing is not recommended as it may cause condensation or micro-crystallization on thawing.
Label Clearly Always label containers with product name, batch number, date of receipt, and storage instructions to maintain lab protocol.
Combining Proscaline with other substances can alter its chemical behavior and introduce unknown risks. Mixing should only occur in controlled analytical environments.
Risk of Cross-Reactivity Combining with other tryptamines or phenethylamines may complicate results and create unpredictable data.
Unknown Synergies Proscaline has not been studied extensively in combination with other chemicals. Avoid mixing unless part of a well-documented protocol.
Analytical Integrity To maintain clarity in research outcomes, isolate variables and avoid confounding interactions from polydrug systems.
Safety First Do not mix compounds without appropriate MSDS (Material Safety Data Sheets), lab supervision, and necessary containment protocols.
Solution Stability If preparing liquid solutions, ensure solvents and co-solutes are chemically compatible to avoid precipitation or degradation.
Psycho Plug guarantees that every batch of Proscaline undergoes rigorous lab testing to meet the highest standards of purity and identity verification.
Purity Level: ≥99.5% All inventory must meet or exceed this standard before being cleared for shipment.
Independent Third-Party Labs Testing is conducted offsite by certified laboratories using techniques such as GC-MS and HPLC.
Certificate of Analysis (COA) Available upon request, the COA details the compound’s purity, contaminants, batch number, and testing methodology.
Contaminant Screening We test for heavy metals, residual solvents, and synthesis byproducts to ensure chemical safety.
Batch Verification Every package is traceable to its production batch, allowing verification and quality audits on demand.
Transparency Policy We publish the most recent test summaries on request, empowering customers to make informed decisions.
No. Proscaline is not approved or intended for human consumption. It is classified as a research chemical and sold strictly for forensic, analytical, and laboratory use.
Not FDA-Approved Proscaline has not been evaluated by the FDA or any health authority for medical use, safety, or efficacy.
Toxicological Data Limited Long-term health effects, dosage thresholds, and pharmacokinetics in humans are not well established.
Labeling Compliance All shipments are clearly marked “Not for Human Consumption” to comply with international and import guidelines.
Professional Use Only Only qualified researchers or institutions with knowledge of chemical handling should work with this compound.
Legal Implications Consumption could lead to legal consequences under analog laws, even if the compound is not scheduled.
In documented research and analytical studies, Proscaline is observed to have an extended duration of action when compared to similar phenethylamines. The full effects unfold gradually and may persist for many hours depending on dosage and metabolism.
Primary Duration Effects typically last 10 to 16 hours, with peak phases occurring between hours 2 and 6, followed by a gradual tapering.
Aftereffects Window Mild psychological or emotional effects (commonly called the “afterglow”) can linger for up to 24 hours post-administration in observational protocols.
Comparison to Mescaline Proscaline has a longer and more gradual onset than mescaline, with a more sustained plateau in most subjective reports.
Variable Based on Dose Larger research doses tend to produce more extended experiences, while smaller quantities reduce both intensity and duration.
Metabolic Considerations Duration can vary slightly based on individual enzyme efficiency and whether the compound is co-administered with other substances in lab protocols.
Importance of Planning Due to its long duration, research sessions involving Proscaline require adequate time allocation and monitoring to observe complete return to baseline.
Yes, research indicates that Proscaline is orally active, and its primary method of administration in lab studies is through oral solution or encapsulation. Its structural similarity to mescaline allows for efficient gastrointestinal absorption.
High Oral Bioavailability It is absorbed well in the digestive tract, resulting in active effects from oral dosing in both capsule and liquid forms.
Delayed Onset Onset generally begins within 60 to 120 minutes post-ingestion, depending on stomach contents and metabolic rate.
No Need for Metabolic Activation Unlike prodrugs, Proscaline does not require transformation by the liver to become psychoactive.
Common in Analytical Settings Capsules or measured liquid solutions are often used in structured lab protocols due to ease of standardization.
Stability in Solution Proscaline can be dissolved in ethanol or DMSO for accurate volumetric dosing when performing chemical assays or biological response tests.
Psycho Plug ensures that every unit of Proscaline is packaged for maximum stability, discretion, and longevity. Proper packaging safeguards the product during both transit and extended storage.
Vacuum-Sealed Foil Bags Default packaging includes odor-proof, air-tight foil bags that are heat-sealed for maximum protection.
Amber Glass Vials For higher-end purchases or special requests, we offer amber glass vials that protect from light and oxygen exposure.
Double Packaging for Stealth All products are placed inside a secondary layer of generic, tamper-proof external packaging for discretion and safety.
No Branding or Product Labels Outer packaging is plain, with no product name, company branding, or content description — ideal for secure import and privacy.
Custom Bulk Packaging Institutions or recurring customers can request bulk quantities with tailored packaging suited for long-term lab storage.
When used appropriately in a laboratory setting with proper equipment, Proscaline is generally safe to handle. As with all chemical substances, it requires adherence to strict handling protocols.
Use Personal Protective Equipment (PPE) Always wear gloves, lab coats, and protective eyewear when working with Proscaline to prevent dermal exposure.
Work in a Ventilated Area Handling should take place in a clean, well-ventilated environment or fume hood to avoid accidental inhalation of fine particles.
Avoid Cross-Contamination Use clean, sterilized tools when transferring Proscaline between containers to maintain purity and experimental integrity.
Label Containers Clearly Ensure all containers used during research are labeled with the compound name, concentration, and hazard class if applicable.
Clean Up Spills Immediately In the event of a spill, clean using dry absorbent material, and follow chemical waste disposal procedures.
Keep Away from Unauthorized Personnel Only trained individuals should have access to Proscaline, and all material must be secured after each session.
Yes. Every order placed with Psycho Plug comes with full shipment tracking, allowing customers to monitor the progress of their package in real-time.
Tracking Provided on Dispatch Once your payment is confirmed and your package is shipped, you’ll receive a tracking number via email.
International Coverage Tracking is available for both domestic and international shipments. Most carriers provide regular scan updates.
Courier Platforms Supported We use reputable couriers such as FedEx, DHL, UPS, and local partners — all integrated with global tracking portals.
24/7 Monitoring Our system is monitored, and any abnormal shipping activity is flagged so we can proactively assist or reship as needed.
Estimated Delivery Windows Domestic deliveries arrive within 1–2 days. International orders typically take 3–7 days depending on customs clearance.
Discreet Shipping Confirmations Your shipping confirmation email contains only generic references — no product names or vendor indicators are ever used.
At Psycho Plug, we understand the risks involved in international shipping of research materials. That’s why we provide a generous, customer-focused resolution policy if your order is seized by customs.
Full Reship or Refund Guarantee If your package is seized, we will offer either a full refund or a one-time reshipment of the same order.
Customer Support Required Simply contact our support team with your order ID and a screenshot or scan of the seizure notice (if available).
Fast Resolution Once verified, replacement orders are prioritized and usually processed within 48 hours.
Seizure Prevention Measures We optimize our stealth packaging, avoid keywords, and use carrier-specific knowledge to reduce seizure rates.
High Success Rate Less than 1% of our orders are seized due to our stealth protocols and region-based shipping strategies.
Customs Advisory Service We may recommend alternative shipping addresses or countries based on your location’s seizure history.
Yes. Proscaline is chemically and pharmacologically similar to mescaline but exhibits notable differences in potency, duration, and subjective profile. It is part of the same chemical family but offers unique properties in research.
Structural Similarity Both are 3,5-dimethoxyphenethylamines, but Proscaline has a propoxy group at the 4-position instead of a methoxy group.
Enhanced Duration Proscaline often lasts longer than mescaline, with a slower onset and smoother decline.
Altered Potency Anecdotal studies suggest Proscaline is slightly more potent on a per milligram basis, requiring less material for comparable effects.
Differences in Subjective Effects Mescaline is known for emotional depth and spiritual intensity, while Proscaline may lean toward visual richness and cognitive engagement.
Availability and Legality Mescaline is illegal in many jurisdictions, while Proscaline remains unscheduled in several regions, making it more accessible for research.
Psycho Plug provides a 30-day return or replacement policy, ensuring complete satisfaction with every order. Our return policy applies even if you change your mind — as long as the package remains sealed and untampered.
Return Eligibility Items must be in their original condition, unopened, and sealed to qualify for return or refund.
Initiate Within 30 Days You must contact us within 30 calendar days of receiving your order to begin the return process.
No Restocking Fee We don’t charge restocking fees. We believe in a fair return policy that puts researchers first.
Customer Pays Return Shipping Return shipping is handled by the customer unless the return is due to a defect or our error.
Refund Processing Time Once we receive and inspect the returned package, refunds are processed within 3–5 business days.
Reship Option Available If you prefer, we can reship the product instead of issuing a refund, depending on your research needs.
Yes. Psycho Plug offers competitive pricing and custom discounts on bulk Proscaline orders, tailored to individual or institutional buyers who require larger quantities.
Tiered Pricing Structure Discounts start at 5g and scale upward. The more you order, the greater the discount per gram.
Institutional Invoicing We provide formal quotes and invoices for universities, research labs, and authorized entities.
Custom Packaging for Bulk Larger orders are packaged in secure, professional-grade containers for long-term lab storage.
Direct Support for Recurring Orders Repeat customers get assigned account managers and dedicated support to streamline bulk ordering.
Private Access to Inventory For frequent bulk buyers, we can reserve stock or notify you in advance when new batches are available.
Request a Quote Contact our support team for personalized pricing based on quantity, destination, and delivery frequency.
TMA-2 and Proscaline are both phenethylamines but differ significantly in structure, pharmacology, and research use. Understanding these differences is crucial for scientific clarity.
Chemical Backbone Proscaline is a phenethylamine with a propoxy group, while TMA-2 is a trimethoxyamphetamine with a methylated alpha carbon, altering its stimulant properties.
Duration and Onset TMA-2 typically has a shorter duration (6–10 hours) and a faster onset, whereas Proscaline is slower to activate but lasts longer.
Receptor Binding TMA-2 is more stimulating and amphetamine-like, while Proscaline exhibits a more classic psychedelic profile, resembling mescaline.
Subjective Differences TMA-2 produces sharper mental stimulation and edge, whereas Proscaline leans toward emotional openness and visual depth.
Legality TMA-2 is scheduled in several countries, including the US. Proscaline remains legally accessible in more regions.
Preferred Research Use Proscaline is more commonly studied in the context of visual and cognitive psychedelic research, while TMA-2 is sometimes included in stimulant-psychotropic crossover studies.
Proscaline: Stimulating Mescaline Analog with Emotional Clarity
Proscaline offers clean, stimulating energy and emotional uplift with light visuals. It’s ideal for daytime journeys, social bonding, and nature immersion. Less hallucinogenic than mescaline but equally warming and mood-brightening.
When you [buy Proscaline online], you’re accessing a psychedelic with stimulating visuals, tactile enhancement, and emotional warmth. As a synthetic cousin to mescaline, Proscaline allows for structured research with predictable onset, making it useful in experimental psychedelic studies.
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